Is it possible to install APIClone on a mac running Mac OS X Catalina?

I'd guess that APIClone can run on pretty much any machine you can run Python on. Though I would like to note that I've never used Mac OS on a personal machine yet so idk much about it (I've been wanting to set up a hackintosh and learn about the system but have been too lazy).

While I have never tried it, since macOS Catalina is officially supported by the latest version of Python, I can safely say that yes, it will work. As chipmunk said, APIClone runs on just about anything that can run modern Python, and the only dependency that isn't fully written in Python is Pillow, used for resizing thumbnails, which of course supports macOS. I'm just mentioning it since I had problems with it while setting up APIClone on Wii Linux.